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BMCBI
2010
89views more  BMCBI 2010»
15 years 4 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2010
156views more  BMCBI 2010»
15 years 4 months ago
Adaptive coarse-grained Monte Carlo simulation of reaction and diffusion dynamics in heterogeneous plasma membranes
Background: An adaptive coarse-grained (kinetic) Monte Carlo (ACGMC) simulation framework is applied to reaction and diffusion dynamics in inhomogeneous domains. The presented mod...
Stuart Collins, Michail Stamatakis, Dionisios G. V...
BMCBI
2008
177views more  BMCBI 2008»
15 years 4 months ago
Baseline Correction for NMR Spectroscopic Metabolomics Data Analysis
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
Yuanxin Xi, David M. Rocke
BMCBI
2008
82views more  BMCBI 2008»
15 years 4 months ago
Standardized high-throughput evaluation of cell-based compound screens
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...
Peter Frommolt, Roman K. Thomas
BMCBI
2007
135views more  BMCBI 2007»
15 years 4 months ago
RECOVIR: An application package to automatically identify some single stranded RNA viruses using capsid protein residues that un
Background: Most single stranded RNA (ssRNA) viruses mutate rapidly to generate large number of strains having highly divergent capsid sequences. Accurate strain recognition in un...
Dianhui Zhu, George E. Fox, Sugoto Chakravarty
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