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BMCBI
2010
144views more  BMCBI 2010»
14 years 12 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...
BMCBI
2010
135views more  BMCBI 2010»
14 years 12 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
BMCBI
2010
205views more  BMCBI 2010»
14 years 12 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2008
110views more  BMCBI 2008»
14 years 12 months ago
Determining significance of pairwise co-occurrences of events in bursty sequences
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Niina Haiminen, Heikki Mannila, Evimaria Terzi
BMCBI
2007
100views more  BMCBI 2007»
14 years 12 months ago
SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)
Background: The need to build a tool to facilitate the quick creation and editing of models encoded in the Systems Biology Markup language (SBML) has been growing with the number ...
Nicolas Rodriguez, Marco Donizelli, Nicolas Le Nov...
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