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BMCBI
2010
123views more  BMCBI 2010»
14 years 4 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BIOINFORMATICS
2011
14 years 4 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
IANDC
2011
129views more  IANDC 2011»
14 years 4 months ago
Rigid tree automata and applications
We introduce the class of Rigid Tree Automata (RTA), an extension of standard bottom-up automata on ranked trees with distinguished states called rigid. Rigid states define a res...
Florent Jacquemard, Francis Klay, Camille Vacher
JCC
2011
133views more  JCC 2011»
14 years 4 months ago
MIBPB: A software package for electrostatic analysis
: The Poisson–Boltzmann equation (PBE) is an established model for the electrostatic analysis of biomolecules. The development of advanced computational techniques for the soluti...
Duan Chen, Zhan Chen, Changjun Chen, Weihua Geng, ...
NAR
2011
331views Computer Vision» more  NAR 2011»
14 years 4 months ago
Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource
The Community Cyberinfrastructure for Advanced Microbial Ecology Research and Analysis (CAMERA, http://camera.calit2.net/) is a database and associated computational infrastructur...
Shulei Sun, Jing Chen, Weizhong Li, Ilkay Altintas...
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