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» Tissue classification with gene expression profiles
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NAR
2011
219views Computer Vision» more  NAR 2011»
14 years 2 months ago
SCLD: a stem cell lineage database for the annotation of cell types and developmental lineages
Stem cell biology has experienced explosive growth over the past decade as researchers attempt to generate therapeutically relevant cell types in the laboratory. Recapitulation of...
Edward Hemphill, Asav P. Dharia, Chih Lee, Carolin...
BMCBI
2005
178views more  BMCBI 2005»
14 years 11 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
14 years 11 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
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BMCBI
2008
117views more  BMCBI 2008»
14 years 11 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2010
160views more  BMCBI 2010»
14 years 11 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...