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» Topological Persistence and Simplification
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BMCBI
2011
13 years 4 months ago
Shape-based peak identification for ChIP-Seq
Background: The identification of binding targets for proteins using ChIP-Seq has gained popularity as an alternative to ChIP-chip. Sequencing can, in principle, eliminate artifac...
Valerie Hower, Steven N. Evans, Lior Pachter
COMPGEOM
2006
ACM
14 years 22 days ago
I/O-efficient batched union-find and its applications to terrain analysis
Despite extensive study over the last four decades and numerous applications, no I/O-efficient algorithm is known for the union-find problem. In this paper we present an I/O-effic...
Pankaj K. Agarwal, Lars Arge, Ke Yi
SODA
2008
ACM
118views Algorithms» more  SODA 2008»
13 years 10 months ago
Geodesic Delaunay triangulation and witness complex in the plane
We introduce a new feature size for bounded domains in the plane endowed with an intrinsic metric. Given a point x in a domain X, the homotopy feature size of X at x measures half...
Jie Gao, Leonidas J. Guibas, Steve Oudot, Yue Wang
ALGORITHMICA
2005
225views more  ALGORITHMICA 2005»
13 years 9 months ago
Better Alternatives to OSPF Routing
The current standard for intra-domain network routing, Open Shortest Path First (OSPF), suffers from a number of problems--the tunable parameters (the weights) are hard to optimiz...
Jessica H. Fong, Anna C. Gilbert, Sampath Kannan, ...