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» Towards an automatic classification of protein structural do...
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NAR
2008
122views more  NAR 2008»
13 years 6 months ago
SIMAP - structuring the network of protein similarities
Protein sequences are the most important source of evolutionary and functional information for new proteins. In order to facilitate the computationally intensive tasks of sequence...
Thomas Rattei, Patrick Tischler, Roland Arnold, Fr...
RECOMB
2003
Springer
14 years 6 months ago
Approximation of protein structure for fast similarity measures
It is shown that structural similarity between proteins can be decided well with much less information than what is used in common similarity measures. The full C representation c...
Fabian Schwarzer, Itay Lotan
BMCBI
2004
125views more  BMCBI 2004»
13 years 6 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
IJBRA
2008
63views more  IJBRA 2008»
13 years 6 months ago
Protein cavity clustering based on community structure of pocket similarity network
: Functions of a protein are mainly determined by its structure. Surface cavities, also called pockets or clefts, are ordinarily regarded as potentially active sites where the prot...
Zhi-Ping Liu, Ling-Yun Wu, Yong Wang, Xiang-Sun Zh...
BMCBI
2007
118views more  BMCBI 2007»
13 years 6 months ago
A topological algorithm for identification of structural domains of proteins
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...
Frank Emmert-Streib, Arcady R. Mushegian