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» Transforming Medicine: Genomics, Bioinformatics, and Human H...
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BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2010
138views more  BMCBI 2010»
14 years 9 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2008
104views more  BMCBI 2008»
14 years 9 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
BIOINFORMATICS
2007
88views more  BIOINFORMATICS 2007»
14 years 9 months ago
Maximum likelihood of phylogenetic networks
Horizontal gene transfer (HGT) is believed to be ubiquitous among bacteria, and plays a major role in their genome diversification as well as their ability to develop resistance t...
Guohua Jin, Luay Nakhleh, Sagi Snir, Tamir Tuller
BMCBI
2006
192views more  BMCBI 2006»
14 years 9 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...