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» Transmembrane Segment Prediction from Protein Sequence Data
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NAR
2010
122views more  NAR 2010»
14 years 4 months ago
ELM: the status of the 2010 eukaryotic linear motif resource
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes thr...
Cathryn M. Gould, Francesca Diella, Allegra Via, P...
BMCBI
2004
151views more  BMCBI 2004»
14 years 9 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
ISMB
2000
14 years 11 months ago
Accelerating Protein Classification Using Suffix Trees
Position-specific scoring matrices have been used extensively to recognize highly conserved protein regions. We present a method for accelerating these searches using a suffix tre...
Bogdan Dorohonceanu, Craig G. Nevill-Manning
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
NAR
2011
225views Computer Vision» more  NAR 2011»
14 years 19 days ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...