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» Transmembrane Segment Prediction from Protein Sequence Data
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BMCBI
2008
96views more  BMCBI 2008»
14 years 9 months ago
The value of position-specific scoring matrices for assessment of protein allegenicity
Background: Bioinformatics tools are commonly used for assessing potential protein allergenicity. While these methods have achieved good accuracies for highly conserved sequences,...
Shen Jean Lim, Joo Chuan Tong, Fook Tim Chew, Mart...
SSDBM
2006
IEEE
163views Database» more  SSDBM 2006»
15 years 3 months ago
ACache: Using Caching to Improve the Performance of Multiple Sequence Alignments
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
Xun Tu, Kajal T. Claypool, Cindy X. Chen
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
RECOMB
2010
Springer
14 years 8 months ago
Predicting Nucleosome Positioning Using Multiple Evidence Tracks
Abstract. We describe a probabilistic model, implemented as a dynamic Bayesian network, that can be used to predict nucleosome positioning along a chromosome based on one or more g...
Sheila M. Reynolds, Zhiping Weng, Jeff A. Bilmes, ...
BMCBI
2006
157views more  BMCBI 2006»
14 years 9 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu