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» Transmembrane Segment Prediction from Protein Sequence Data
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BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
NAR
2002
132views more  NAR 2002»
14 years 9 months ago
euGenes: a eukaryote genome information system
euGenes is a genome information system and database that provides a common summary of eukaryote genes and genomes, at web site http://iubio.bio.indiana.edu/eugenes/. Seven popular...
Donald G. Gilbert
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
15 years 4 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...
BMCBI
2006
134views more  BMCBI 2006»
14 years 9 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...