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» Transmembrane Segment Prediction from Protein Sequence Data
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BMCBI
2005
150views more  BMCBI 2005»
14 years 9 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
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BMCBI
2007
133views more  BMCBI 2007»
14 years 9 months ago
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Oscar Conchillo-Solé, Natalia S. de Groot, ...
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
CANDC
2006
ACM
14 years 9 months ago
Prediction of protein subcellular location using hydrophobic patterns of amino acid sequence
The function of eukaryotic protein is closely correlated with its subcellular location. The number of newly found protein sequences entering into data banks is rapidly increasing ...
Tongliang Zhang, Yongsheng Ding, Kuo-Chen Chou
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes