Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...