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75
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BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BMCBI
2008
106views more  BMCBI 2008»
14 years 9 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
BMCBI
2008
80views more  BMCBI 2008»
14 years 9 months ago
Towards an automatic classification of protein structural domains based on structural similarity
Background: Formal classification of a large collection of protein structures aids the understanding of evolutionary relationships among them. Classifications involving manual ste...
Vichetra Sam, Chin-Hsien Tai, Jean Garnier, Jean-F...
78
Voted
BMCBI
2006
118views more  BMCBI 2006»
14 years 9 months ago
A graphical model approach to automated classification of protein subcellular location patterns in multi-cell images
Background: Knowledge of the subcellular location of a protein is critical to understanding how that protein works in a cell. This location is frequently determined by the interpr...
Shann-Ching Chen, Robert F. Murphy
TASLP
2008
201views more  TASLP 2008»
14 years 9 months ago
Syntactically Lexicalized Phrase-Based SMT
Abstract--Until quite recently, extending Phrase-based Statistical Machine Translation (PBSMT) with syntactic knowledge caused system performance to deteriorate. The most recent su...
Hany Hassan, Khalil Sima'an, Andy Way