Sciweavers

226 search results - page 38 / 46
» Two-Level Interaction Approach for Transfer Function Specifi...
Sort
View
BMCBI
2007
102views more  BMCBI 2007»
14 years 12 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BMCBI
2010
139views more  BMCBI 2010»
14 years 12 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
SAC
2004
ACM
15 years 5 months ago
Combining analysis and synthesis in a model of a biological cell
for ideas, and then abstract away from these ideas to produce algorithmic processes that can create problem solutions in a bottom-up manner. We have previously described a top-dow...
Ken Webb, Tony White
BMCBI
2008
152views more  BMCBI 2008»
14 years 12 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
TOG
2002
128views more  TOG 2002»
14 years 11 months ago
Modelling with implicit surfaces that interpolate
We introduce new techniques for modelling with interpolating implicit surfaces. This form of implicit surface was first used for problems of surface reconstruction [24] and shape ...
Greg Turk, James F. O'Brien