4 search results - page 1 / 1 » Two-part permutation tests for DNA methylation and microarra... |
BMCBI
2005
15 years 7 days ago
2005
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
103
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BMCBI
2008
15 years 14 days ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
117
Voted
BMCBI
2010
15 years 14 days ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
108
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BMCBI
2007
15 years 11 days ago
2007
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...