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» Two-phase clustering strategy for gene expression data sets
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GECCO
2005
Springer
127views Optimization» more  GECCO 2005»
15 years 3 months ago
Identifying valid solutions for the inference of regulatory networks
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. The problem often is multi-modal and therefore appropriate optimi...
Christian Spieth, Felix Streichert, Nora Speer, An...
82
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IDA
2005
Springer
15 years 2 months ago
From Local Pattern Mining to Relevant Bi-cluster Characterization
Clustering or bi-clustering techniques have been proved quite useful in many application domains. A weakness of these techniques remains the poor support for grouping characterizat...
Ruggero G. Pensa, Jean-François Boulicaut
BMCBI
2006
131views more  BMCBI 2006»
14 years 9 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
BMCBI
2007
116views more  BMCBI 2007»
14 years 9 months ago
Ranked Adjusted Rand: integrating distance and partition information in a measure of clustering agreement
Background: Biological information is commonly used to cluster or classify entities of interest such as genes, conditions, species or samples. However, different sources of data c...
Francisco R. Pinto, João A. Carriço,...
BMCBI
2010
154views more  BMCBI 2010»
14 years 6 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...