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» USPEX - Evolutionary crystal structure prediction
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BMCBI
2010
116views more  BMCBI 2010»
14 years 11 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2010
105views more  BMCBI 2010»
14 years 11 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
WCE
2007
15 years 24 days ago
High energy white beam x-ray diffraction studies of residual strains in engineering components
— In order to predict the durability of engineering components and improve performance, it is mandatory to understand residual stresses. The last decade has witnessed a significa...
Shu Yan Zhang, Willem J. J. Vorster, Tea-Sung Jun,...
BMCBI
2005
103views more  BMCBI 2005»
14 years 11 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate