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BMCBI
2010
175views more  BMCBI 2010»
14 years 10 months ago
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services
Background: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers. Tools can be made to fle...
Martijn P. van Iersel, Alexander R. Pico, Thomas K...
BMCBI
2010
147views more  BMCBI 2010»
14 years 10 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BMCBI
2007
167views more  BMCBI 2007»
14 years 10 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
BMCBI
2007
176views more  BMCBI 2007»
14 years 10 months ago
Correlation-maximizing surrogate gene space for visual mining of gene expression patterns in developing barley endosperm tissue
Background: Micro- and macroarray technologies help acquire thousands of gene expression patterns covering important biological processes during plant ontogeny. Particularly, fait...
Marc Strickert, Nese Sreenivasulu, Björn Usad...
BMCBI
2008
77views more  BMCBI 2008»
14 years 10 months ago
Stochastic models for the in silico simulation of synaptic processes
Background: Research in life sciences is benefiting from a large availability of formal description techniques and analysis methodologies. These allow both the phenomena investiga...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...