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» Unbiased pattern detection in microarray data series
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AAAI
2008
15 years 11 hour ago
Ensemble Forecasting for Disease Outbreak Detection
We describe a method to improve detection of disease outbreaks in pre-diagnostic time series data. The method uses multiple forecasters and learns the linear combination to minimi...
Thomas H. Lotze, Galit Shmueli
ITA
2006
167views Communications» more  ITA 2006»
14 years 9 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
DATAMINE
2008
219views more  DATAMINE 2008»
14 years 9 months ago
Correlating burst events on streaming stock market data
Abstract We address the problem of monitoring and identification of correlated burst patterns in multi-stream time series databases. We follow a two-step methodology: first we iden...
Michail Vlachos, Kun-Lung Wu, Shyh-Kwei Chen, Phil...
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BMCBI
2007
126views more  BMCBI 2007»
14 years 9 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...