Binary subcomplexes in proteins database (BISC) is a new protein–protein interaction (PPI) database linking up the two communities most active in their characterization: structu...
We implement a weighted negative update of the covariance matrix in the CMA-ES—weighted active CMA-ES or, in short, aCMA-ES. We benchmark the IPOP-aCMA-ES and compare the perfor...
Several implementations of Artificial Neural Networks have been reported in scientific papers. Nevertheless, these implementations do not allow the direct use of off-line trained n...
Pedro Ferreira, Pedro Ribeiro, Ana Antunes, Fernan...
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...