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124
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BMCBI
2010
128views more  BMCBI 2010»
15 years 3 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
144
Voted
BMCBI
2008
144views more  BMCBI 2008»
15 years 3 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...
130
Voted
BMCBI
2008
97views more  BMCBI 2008»
15 years 3 months ago
SiteSeek: Post-translational modification analysis using adaptive locality-effective kernel methods and new profiles
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
116
Voted
BMCBI
2006
172views more  BMCBI 2006»
15 years 3 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
JMIV
2006
176views more  JMIV 2006»
15 years 3 months ago
Segmentation of Vectorial Image Features Using Shape Gradients and Information Measures
In this paper, we propose to focus on the segmentation of vectorial features (e.g. vector fields or color intensity) using region-based active contours. We search for a domain that...
Ariane Herbulot, Stéphanie Jehan-Besson, St...