1003 search results - page 126 / 201 » Understanding Availability |
BMCBI
2006
2006
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
14 years 11 months ago
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
120
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BMCBI
2006
14 years 11 months ago
2006
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
BMCBI
2005
14 years 11 months ago
2005
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
106
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BMCBI
2005
14 years 11 months ago
2005
Background: Recent advances in molecular biology techniques provide an opportunity for developing detailed mathematical models of biological processes. An iterative scheme is intr...
BMCBI
2004
14 years 11 months ago
2004
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...