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BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-or
Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...
BMCBI
2010
218views more  BMCBI 2010»
14 years 9 months ago
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Background: Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...
Michael Scharfe, Rainer Pielot, Falk Schreiber
BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
14 years 9 months ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
BMCBI
2010
103views more  BMCBI 2010»
14 years 9 months ago
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
Inkyung Jung, Akihisa Matsuyama, Minoru Yoshida, D...
BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
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