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BMCBI
2010
105views more  BMCBI 2010»
14 years 11 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
BMCBI
2007
110views more  BMCBI 2007»
14 years 11 months ago
Analysis of feedback loops and robustness in network evolution based on Boolean models
Background: Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degr...
Yung-Keun Kwon, Kwang-Hyun Cho
BMCBI
2007
107views more  BMCBI 2007»
14 years 11 months ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
CORR
2010
Springer
82views Education» more  CORR 2010»
14 years 11 months ago
Expansion and Search in Networks
Borrowing from concepts in expander graphs, we study the expansion properties of real-world, complex networks (e.g. social networks, unstructured peer-to-peer or P2P networks) and...
Arun S. Maiya, Tanya Y. Berger-Wolf
BMCBI
2006
144views more  BMCBI 2006»
14 years 11 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...