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ICSM
2009
IEEE
14 years 8 months ago
Decomposing object-oriented class modules using an agglomerative clustering technique
Software can be considered a live entity, as it undergoes many alterations throughout its lifecycle. Furthermore, developers do not usually retain a good design in favor of adding...
Marios Fokaefs, Nikolaos Tsantalis, Alexander Chat...
84
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BMCBI
2010
142views more  BMCBI 2010»
14 years 7 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
BCB
2010
150views Bioinformatics» more  BCB 2010»
14 years 5 months ago
Enzymatic target identification with dynamic states
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
Bin Song, Sanjay Ranka, Tamer Kahveci
BMCBI
2010
102views more  BMCBI 2010»
14 years 5 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
BMCBI
2011
14 years 5 months ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou