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BMCBI
2010
153views more  BMCBI 2010»
15 years 22 days ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
134
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BMCBI
2010
138views more  BMCBI 2010»
15 years 22 days ago
UFFizi: a generic platform for ranking informative features
Background: Feature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or cluste...
Assaf Gottlieb, Roy Varshavsky, Michal Linial, Dav...
BMCBI
2007
133views more  BMCBI 2007»
15 years 22 days ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
105
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BMCBI
2007
123views more  BMCBI 2007»
15 years 22 days ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BIOINFORMATICS
2006
106views more  BIOINFORMATICS 2006»
15 years 20 days ago
Identification of biochemical networks by S-tree based genetic programming
Motivation: Most previous approaches to model biochemical networks havefocusedeither on the characterization of a networkstructurewith a number of components or on the estimation ...
Dong-Yeon Cho, Kwang-Hyun Cho, Byoung-Tak Zhang