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15 years 6 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
SISAP
2009
IEEE
155views Data Mining» more  SISAP 2009»
15 years 11 months ago
Analyzing Metric Space Indexes: What For?
—It has been a long way since the beginnings of metric space searching, where people coming from algorithmics tried to apply their background to this new paradigm, obtaining vari...
Gonzalo Navarro
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 11 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
GECCO
2007
Springer
159views Optimization» more  GECCO 2007»
15 years 11 months ago
Evolutionary hypernetwork models for aptamer-based cardiovascular disease diagnosis
We present a biology-inspired probabilistic graphical model, called the hypernetwork model, and its application to medical diagnosis of disease. The hypernetwork models are a way ...
JungWoo Ha, Jae-Hong Eom, Sung-Chun Kim, Byoung-Ta...
NPIV
1999
ACM
142views Visualization» more  NPIV 1999»
15 years 9 months ago
ALMOST: Exploring Program Traces
We built a tool to visualize and explore program execution traces. Our goal was to help programmers without any prior knowledge of a program, quickly get enough knowledge about it...
Manos Reniers, Steven P. Reis