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BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
14 years 9 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
BMCBI
2008
14 years 9 months ago
2008
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
BMCBI
2007
14 years 9 months ago
2007
Background: The translation start site plays an important role in the control of translation efficiency of eukaryotic mRNAs. The recognition of the start AUG codon by eukaryotic r...
BMCBI
2010
14 years 9 months ago
2010
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
BMCBI
2008
14 years 9 months ago
2008
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...