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BMCBI
2006
153views more  BMCBI 2006»
14 years 12 months ago
Automatic document classification of biological literature
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...
David Chen, Hans-Michael Müller, Paul W. Ster...
BMCBI
2006
136views more  BMCBI 2006»
14 years 12 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
BMCBI
2006
116views more  BMCBI 2006»
14 years 12 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
93views more  BMCBI 2006»
14 years 12 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
BMCBI
2006
111views more  BMCBI 2006»
14 years 12 months ago
High throughput profile-profile based fold recognition for the entire human proteome
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
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