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BMCBI
2007
162views more  BMCBI 2007»
14 years 9 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2008
100views more  BMCBI 2008»
14 years 9 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
CSCW
2010
ACM
14 years 9 months ago
PeerCare: Supporting Awareness of Rhythms and Routines for Better Aging in Place
Caring for the elderly is becoming a key challenge for society, given the shortage of trained personnel and the increased age of the population. Innovative approaches are needed t...
Yann Riche, Wendy E. Mackay
ASE
2006
106views more  ASE 2006»
14 years 9 months ago
Integrating COTS Software into Systems through Instrumentation and Reasoning
Commercial-off-the-shelf (COTS) software tends to be cheap, reliable, and functionally powerful due to its large user base. It has thus become highly desirable to incorporate COTS ...
Alexander Egyed, Robert Balzer
BMCBI
2006
101views more  BMCBI 2006»
14 years 9 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...