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BIOCOMP
2010
15 years 24 days ago
A Network-based Approach to Classify Disease Stages of Prostate Cancer Using Quantitative Network Measures
Abstract-- This study deals with investigating the classification performance of information-theoretic measures when applied to complex biological networks. In particular, our aim ...
Laurin A. J. Mueller, Karl G. Kugler, Andreas Dand...
BMCBI
2005
155views more  BMCBI 2005»
15 years 3 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley
BMCBI
2007
78views more  BMCBI 2007»
15 years 4 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
CCE
2008
15 years 4 months ago
Prediction of secondary structures of proteins using a two-stage method
Protein structure determination and prediction has been a focal research subject in life sciences due to the importance of protein structure in understanding the biological and ch...
Fadime Üney Yüksektepe, Özlem Yilma...
ICANNGA
2007
Springer
100views Algorithms» more  ICANNGA 2007»
15 years 8 months ago
Softening Splits in Decision Trees Using Simulated Annealing
Predictions computed by a classification tree are usually constant on axis-parallel hyperrectangles corresponding to the leaves and have strict jumps on their boundaries. The densi...
Jakub Dvorák, Petr Savický