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» Using Indirect protein-protein Interactions for protein Comp...
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BMCBI
2010
118views more  BMCBI 2010»
14 years 9 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2006
174views more  BMCBI 2006»
14 years 9 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
ECAL
2007
Springer
15 years 3 months ago
Folding Protein-Like Structures with Open L-Systems
Abstract. Proteins, under native conditions, fold to specific 3D structures according to their 1D amino acid sequence, which in turn is defined by the genetic code. The specific...
Gemma B. Danks, Susan Stepney, Leo S. D. Caves
BMCBI
2006
111views more  BMCBI 2006»
14 years 9 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover
BMCBI
2010
179views more  BMCBI 2010»
14 years 9 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...