Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Background: Protein interactions support cell organization and mediate its response to any specific stimulus. Recent technological advances have produced large data-sets that aim ...
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...