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72
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BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
85
Voted
BMCBI
2006
165views more  BMCBI 2006»
14 years 10 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2006
116views more  BMCBI 2006»
14 years 10 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
SIGCSE
2008
ACM
143views Education» more  SIGCSE 2008»
14 years 10 months ago
Test-driven learning in early programming courses
Coercing new programmers to adopt disciplined development practices such as thorough unit testing is a challenging endeavor. Test-driven development (TDD) has been proposed as a s...
David Janzen, Hossein Saiedian
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