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    » Using Multiple Alignments to Improve Gene Prediction
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    BMCBI
    2005
    162views more  BMCBI 2005»
    Accelerated probabilistic inference of RNA structure evolution
    14 years 11 months ago
    Accelerated probabilistic inference of RNA structure evolution
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    Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
    Ian Holmes
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    BMCBI
    2005
    125views more  BMCBI 2005»
    DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
    14 years 11 months ago
    DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
    Download  www.biomedcentral.com
    Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
    Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
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    BMCBI
    2006
    82views more  BMCBI 2006»
    Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
    14 years 11 months ago
    Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
    Download  www.biomedcentral.com
    Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
    Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
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    BIBE
    2007
    IEEE
    128views Bioinformatics» more  BIBE 2007»
    QOMA2: Optimizing the alignment of many sequences
    15 years 6 months ago
    QOMA2: Optimizing the alignment of many sequences
    Download  www.cise.ufl.edu
    Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
    Xu Zhang, Tamer Kahveci
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    BMCBI
    2006
    186views more  BMCBI 2006»
    Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
    14 years 11 months ago
    Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
    Download  www.biomedcentral.com
    Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
    Xiaoli Li, Yin-Chet Tan, See-Kiong Ng
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