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ICASSP
2010
IEEE
13 years 6 months ago
Graph-spectrum-based neural spike features for stereotrodes and tetrodes
Extracellular recording of neural signals records the action potentials (known as spikes) of neurons adjacent to the electrode as well as the noise generated by the overall neural...
Yasser Ghanbari, Panos Papamichalis, Larry Spence
BMCBI
2008
178views more  BMCBI 2008»
13 years 6 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2007
159views more  BMCBI 2007»
13 years 6 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
BMCBI
2004
146views more  BMCBI 2004»
13 years 6 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
BMCBI
2010
124views more  BMCBI 2010»
13 years 6 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...