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152
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
167
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
150
Voted
KDD
2009
ACM
16 years 4 months ago
2009
ACM
Learning probabilistic graphical models from high-dimensional datasets is a computationally challenging task. In many interesting applications, the domain dimensionality is such a...
124
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
143
Voted
BMCBI
2004
15 years 3 months ago
2004
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...