Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Learning probabilistic graphical models from high-dimensional datasets is a computationally challenging task. In many interesting applications, the domain dimensionality is such a...
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...
Shandar Ahmad, M. Michael Gromiha, Hamed Fawareh, ...