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BMCBI
2008
130views more  BMCBI 2008»
15 years 19 days ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2006
161views more  BMCBI 2006»
15 years 17 days ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
113
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KDD
2009
ACM
191views Data Mining» more  KDD 2009»
16 years 1 months ago
Scalable pseudo-likelihood estimation in hybrid random fields
Learning probabilistic graphical models from high-dimensional datasets is a computationally challenging task. In many interesting applications, the domain dimensionality is such a...
Antonino Freno, Edmondo Trentin, Marco Gori
99
Voted
BMCBI
2010
127views more  BMCBI 2010»
15 years 19 days ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
113
Voted
BMCBI
2004
265views more  BMCBI 2004»
15 years 12 days ago
ASAView: Database and tool for solvent accessibility representation in proteins
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...
Shandar Ahmad, M. Michael Gromiha, Hamed Fawareh, ...