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» Using context to improve protein domain identification
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ISBI
2008
IEEE
15 years 10 months ago
Flexible image registration for the identification of best fitted protein models in 3D-EM maps
In this work we propose an image registration algorithm to automatically fit protein atomic domain models into medium-resolution three-dimensional electron microscopy reconstructi...
Andrés Santos, Carlos Oscar Sánchez ...
BMCBI
2008
110views more  BMCBI 2008»
14 years 10 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
ISMB
1998
14 years 11 months ago
Identification of Divergent Functions in Homologous Proteins by Induction over Conserved Modules
Homologousproteins do not necessarily exhibit identical biochemicalfunction. Despitethis fact, local or global sequence similarity is widely used as an indication of functional id...
Imran Shah, Lawrence Hunter
BMCBI
2007
139views more  BMCBI 2007»
14 years 10 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
BMCBI
2006
111views more  BMCBI 2006»
14 years 10 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...