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» Using context to improve protein domain identification
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REFSQ
2010
Springer
15 years 1 months ago
A Domain Ontology Building Process for Guiding Requirements Elicitation
[Context and motivation] In Requirements Management, ontologies are used to reconcile gaps in the knowledge and common understanding among stakeholders during requirement elicitati...
Inah Omoronyia, Guttorm Sindre, Tor Stålhane...
BIOINFORMATICS
2008
97views more  BIOINFORMATICS 2008»
14 years 10 months ago
An integrated system for studying residue coevolution in proteins
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
Kevin Y. Yip, Prianka Patel, Philip M. Kim, Donald...
BMCBI
2006
133views more  BMCBI 2006»
14 years 10 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
GCB
2009
Springer
154views Biometrics» more  GCB 2009»
15 years 1 months ago
Comparative Identification of Differential Interactions from Trajectories of Dynamic Biological Networks
Abstract: It is often challenging to reconstruct accurately a complete dynamic biological network due to the scarcity of data collected in cost-effective experiments. This paper ad...
Zhengyu Ouyang, Mingzhou Song
BMCBI
2010
178views more  BMCBI 2010»
14 years 10 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...