67 search results - page 11 / 14 » Using gene deletion and gene duplication in evolution strate... |
88
Voted
ISMB
2000
14 years 11 months ago
2000
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
101
click to vote
BMCBI
2006
14 years 9 months ago
2006
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
55
Voted
DNA
2001
Springer
15 years 2 months ago
2001
Springer
The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
BMCBI
2010
14 years 9 months ago
2010
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
BMCBI
2005
14 years 9 months ago
2005
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...