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EUROGP
1999
Springer
105views Optimization» more  EUROGP 1999»
15 years 1 months ago
How to Invent Functions
The paper presents the abstraction transformation which is a fundaethod for creating functions in ADATE. The use of abstraction turns out to be similar to evolution by gene duplic...
Roland Olsson
77
Voted
ICNC
2005
Springer
15 years 3 months ago
Coevolutionary Genetic Algorithms to Simulate the Immune System's Gene Libraries Evolution
Two binary-encoded models describing some aspects of the coevolution between an artificial immune system and a set of antigens have been proposed and analyzed. The first model ha...
Grazziela Patrocinio Figueredo, Luís Alfred...
74
Voted
EPIA
2007
Springer
15 years 3 months ago
Evaluating Simulated Annealing Algorithms in the Optimization of Bacterial Strains
Abstract. In this work, a Simulated Annealing (SA) algorithm is proposed for a Metabolic Engineering task: the optimization of the set of gene deletions to apply to a microbial str...
Miguel Rocha, Rui Mendes, Paulo Maia, José ...
89
Voted
CIBCB
2007
IEEE
14 years 11 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
80
Voted
WABI
2009
Springer
181views Bioinformatics» more  WABI 2009»
15 years 4 months ago
Decoding Synteny Blocks and Large-Scale Duplications in Mammalian and Plant Genomes
Abstract. The existing synteny block reconstruction algorithms use anchors (e.g., orthologous genes) shared over all genomes to construct the synteny blocks for multiple genomes. T...
Qian Peng, Max A. Alekseyev, Glenn Tesler, Pavel A...