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83
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CIKM
2008
Springer
14 years 11 months ago
On effective presentation of graph patterns: a structural representative approach
In the past, quite a few fast algorithms have been developed to mine frequent patterns over graph data, with the large spectrum covering many variants of the problem. However, the...
Chen Chen, Cindy Xide Lin, Xifeng Yan, Jiawei Han
RECOMB
2010
Springer
14 years 11 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
87
Voted
BMCBI
2010
138views more  BMCBI 2010»
14 years 9 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
90
Voted
BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
Seahawk: moving beyond HTML in Web-based bioinformatics analysis
Background: Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining multiple ...
Paul M. K. Gordon, Christoph W. Sensen
91
Voted
BMCBI
2007
134views more  BMCBI 2007»
14 years 9 months ago
PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Ji He, Xinbin Dai, Xuechun Zhao