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BMCBI
2006
86views more  BMCBI 2006»
15 years 4 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
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BMCBI
2006
114views more  BMCBI 2006»
15 years 4 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
154views more  BMCBI 2006»
15 years 4 months ago
Automated recognition of malignancy mentions in biomedical literature
Background: The rapid proliferation of biomedical text makes it increasingly difficult for researchers to identify, synthesize, and utilize developed knowledge in their fields of ...
Yang Jin, Ryan T. McDonald, Kevin Lerman, Mark A. ...
BMCBI
2006
116views more  BMCBI 2006»
15 years 4 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2006
100views more  BMCBI 2006»
15 years 4 months ago
Empirical array quality weights in the analysis of microarray data
Background: Assessment of array quality is an essential step in the analysis of data from microarray experiments. Once detected, less reliable arrays are typically excluded or &qu...
Matthew E. Ritchie, Dileepa S. Diyagama, Jody Neil...
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