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BMCBI
2007
157views more  BMCBI 2007»
14 years 10 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
BMCBI
2008
126views more  BMCBI 2008»
14 years 10 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
BMCBI
2010
187views more  BMCBI 2010»
14 years 10 months ago
PathEx: a novel multi factors based datasets selector web tool
Background: Microarray experiments have become very popular in life science research. However, if such experiments are only considered independently, the possibilities for analysi...
Eric Bareke, Michael Pierre, Anthoula Gaigneaux, B...
BMCBI
2010
115views more  BMCBI 2010»
14 years 10 months ago
Assessment and optimisation of normalisation methods for dual-colour antibody microarrays
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Martin Sill, Christoph Schroder, Jörg D. Hohe...
BMCBI
2008
186views more  BMCBI 2008»
14 years 10 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
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