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» Using sampling methods to improve binding site predictions
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125
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CSB
2003
IEEE
124views Bioinformatics» more  CSB 2003»
15 years 5 months ago
SMASHing regulatory sites in DNA by human
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
106
Voted
ICGA
1997
122views Optimization» more  ICGA 1997»
15 years 1 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
CSB
2005
IEEE
149views Bioinformatics» more  CSB 2005»
15 years 6 months ago
Combinatorial method of splice sites prediction
Predicting and proper ranking of splice sites (SS) is a challenging problem in bioinformatics and machine learning communities. Proposed method of donor and acceptor SSs predictio...
Alexander G. Churbanov, Hesham H. Ali
100
Voted
BMCBI
2007
97views more  BMCBI 2007»
15 years 17 days ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2005
130views more  BMCBI 2005»
15 years 10 days ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...