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» Using sampling methods to improve binding site predictions
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IWMM
2004
Springer
98views Hardware» more  IWMM 2004»
15 years 5 months ago
Dynamic object sampling for pretenuring
Many state-of-the-art garbage collectors are generational, collecting the young nursery objects more frequently than old objects. These collectors perform well because young objec...
Maria Jump, Stephen M. Blackburn, Kathryn S. McKin...
CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
15 years 4 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...
89
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BMCBI
2007
114views more  BMCBI 2007»
15 years 14 days ago
Combination of scoring schemes for protein docking
Background: Docking algorithms are developed to predict in which orientation two proteins are likely to bind under natural conditions. The currently used methods usually consist o...
Philipp Heuser, Dietmar Schomburg
92
Voted
BMCBI
2006
134views more  BMCBI 2006»
15 years 16 days ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
APBC
2004
116views Bioinformatics» more  APBC 2004»
15 years 1 months ago
Structure-Function Relationship in DNA Sequence Recognition by Transcription Factors
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...