259 search results - page 23 / 52 » Using sampling methods to improve binding site predictions |
114
Voted
BIBM
2008
IEEE
15 years 7 months ago
2008
IEEE
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
107
Voted
BMCBI
2008
15 years 18 days ago
2008
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
106
Voted
ISSRE
2005
IEEE
15 years 6 months ago
2005
IEEE
The software development process imposes major impacts on the quality of software at every development stage; therefore, a common goal of each software development phase concerns ...
101
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ICML
2007
IEEE
16 years 1 months ago
2007
IEEE
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
100
Voted
BMCBI
2007
15 years 18 days ago
2007
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...