259 search results - page 26 / 52 » Using sampling methods to improve binding site predictions |
BMCBI
2006
15 years 16 days ago
2006
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
130
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BMCBI
2010
14 years 7 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
77
Voted
BMCBI
2005
15 years 11 days ago
2005
Background: In the post-genomic era, correct gene prediction has become one of the biggest challenges in genome annotation. Improved promoter prediction methods can be one step to...
118
Voted
BMCBI
2005
15 years 11 days ago
2005
Background: In the clinical context, samples assayed by microarray are often classified by cell line or tumour type and it is of interest to discover a set of genes that can be us...
128
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PRIB
2009
Springer
15 years 7 months ago
2009
Springer
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling. We present a knowledge-guided approach for docking protein dom...