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» Using sampling methods to improve binding site predictions
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100
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BMCBI
2008
145views more  BMCBI 2008»
15 years 18 days ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
125
Voted
CDC
2008
IEEE
126views Control Systems» more  CDC 2008»
15 years 2 months ago
Subspace identification using predictor estimation via Gaussian regression
In this paper we propose a new nonparametric approach to identification of linear time invariant systems using subspace methods. The nonparametric paradigm to prediction of station...
Alessandro Chiuso, Gianluigi Pillonetto, Giuseppe ...
96
Voted
BMCBI
2010
86views more  BMCBI 2010»
15 years 18 days ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
112
Voted
BMCBI
2006
117views more  BMCBI 2006»
15 years 16 days ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2010
133views more  BMCBI 2010»
15 years 18 days ago
Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
Shandar Ahmad, Yumlembam Hemjit Singh, Yogesh Paud...