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172
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BMCBI
2004
15 years 4 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
132
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BMCBI
2004
15 years 4 months ago
2004
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
148
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BMCBI
2004
15 years 4 months ago
2004
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
150
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BMCBI
2004
15 years 4 months ago
2004
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
159
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BMCBI
2004
15 years 4 months ago
2004
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...